Genealogical tree and skyline plots of coalescent statistics for sequences simulated under episodic positive selection. There were 10,000 individuals in the simulation, and an advantageous mutation rate μa of 8 × 10-7 per individual per generation with each mutation harboring a selective advantage s of 0.1. The tree shown represents the maximum posterior tree sampled over the course of the MCMC analysis of the simulated data. Colors move from purple to red as fitness increases. For coalescent statistics, TMRCA, diversity and Neτ, solid lines represent mean values and gray outlines represent 95% credible intervals across MCMC replicates. TMRCA, diversity and Neτ are measured in units of generations.
Bedford et al. BMC Evolutionary Biology 2011 11:220 doi:10.1186/1471-2148-11-220