Table 6

Summary of defined alignment borders

DMT

Jack DL, Yang NM, Saier MH, Jr. (2001)

Pfam architecture

Frequency of architecture

New TM structure


Cation efflux

N/A

4-LC-2

96%

4+2

EamA

N/A

5+5

44%

5+5

DUF803

N/A

(1)+4

80%

4+5

DUF914

N/A

7+0

88%

5+5

DUF1632

9-10 TM

5+(3)

80%

5+5

NST

10 TM

(2)+6

97%

5+5

TPT

6-9 TM

(EamA)+4

77%

0+5

UAA

10 TM

3-LC-1-LC-5

93%

5+5

UPF0546

N/A

2+0

96%

4+0

Zip

N/A

2-LC-1-LC-1-2

93%

3+5


This table lists for human DMT families from [additional file 2: supplementary table S2], the evidence provided by Jack DL, Yang NM, Saier MH, Jr. (2001), and the Pfam dominant architecture and prevalence, and the TM structure recommended using evidence type from [additional file 5: supplementary table S4]. The parentheses in the Pfam architecture column indicate TMs or unrelated domains not covered by the Pfam-A hit to the current DMT.

Västermark et al. BMC Evolutionary Biology 2011 11:123   doi:10.1186/1471-2148-11-123

Open Data