Maximum likelihood tree of the anoctamin protein family. The phylogenetic tree constructed with the program PhyML shows the evolutionary relationship of the anoctamin protein family. Several possible duplication time points are indicated with black arrows. Non-vertebrate anoctamins are depicted with red color. The unit of branch length is the expected fraction of amino acids substitution.
Milenkovic et al. BMC Evolutionary Biology 2010 10:319 doi:10.1186/1471-2148-10-319