Figure 3.

Analysis of SNP located in the genomic region encompassing CD28 and CTLA4. SNPs significantly associated with helminth diversity are shown in red while the region covered by CD28 and CTLA4 are shown in blue. The location of DNAse hypersensitive sites in CD4⁺ T cells is shown in gray while recombination hotspots are in black. The image was generated by using the "add custom track" utility available through the UCSC Genome Browser.