Research article

A comprehensive survey of human polymorphisms at conserved splice dinucleotides and its evolutionary relationship with alternative splicing

Makoto K Shimada^1,^2,³, Yosuke Hayakawa^2,⁴, Jun-ichi Takeda^1,², Takashi Gojobori^1,⁵ and Tadashi Imanishi¹^*

¹ Biomedicinal Information Research Center, National Institute of Advanced Industrial Science and Technology, 2-42 Aomi Koto-ku, Tokyo135-0064, Japan

² Japan Biological Informatics Consortium, 10F TIME24 Building, 2-45 Aomi, Koto-ku, Tokyo 135-0064, Japan

³ Institute for Comprehensive Medical Science, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan

⁴ Hitachi Software Engineering Co., Ltd., 1-1-43 Suehirocho, Tsurumi-ku, Yokohama 230-0045, Japan

⁵ Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, Japan

For all author emails, please log on.

BMC Evolutionary Biology 2010, 10:122 doi:10.1186/1471-2148-10-122

Published: 30 April 2010

Additional file 1:

Supplemental tables. Zip file containing the supplemental tables and their legends.

Format: ZIP Size: 16KB Download file