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Open AccessResearch article

Identifying candidate genes affecting developmental time in Drosophila melanogaster: pervasive pleiotropy and gene-by-environment interaction

Julián Mensch email, Nicolás Lavagnino email, Valeria Paula Carreira email, Ana Massaldi email, Esteban Hasson email and Juan José Fanara email

Departamento de Ecología, Genética y Evolución, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina

author email corresponding author email

BMC Developmental Biology 2008, 8:78doi:10.1186/1471-213X-8-78

Published: 8 August 2008

Additional files

Additional file 1:

Correlation between viability (VT) and developmental time (DT) for all P[GT1] insertion lines analyzed. VT is presented in angular transformation (arcsine of the square root of the proportion of survival) and DT expressed in hours. Solid line represents the correlation plot and dashed lines the 95% confidence intervals (r = 0.305).

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Additional file 2:

Mean values of significant P[GT1] insertion lines on DT (25°C). Values are shown as the deviation of the insertion line mean from contemporaneous control for each sex separately.

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Additional file 3:

Genetic information of candidate DT genes including gene names, P[GT1] insertion sites, cytologial positions, biological process gene-ontologies and pleiotropy.

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