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The migration of paraxial and lateral plate mesoderm cells emerging from the late primitive streak is controlled by different Wnt signals

Dylan Sweetman1 email, Laura Wagstaff2 email, Oliver Cooper1,3 email, Cornelis Weijer4 email and Andrea Münsterberg1 email

School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK

Biomedical Research Centre, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK

Centre for Neuroregeneration Research, Harvard Medical School, McLean Hospital, Belmont, MA 02478, USA

College of Life Sciences Biocentre, MSI/WTB complex, University of Dundee, Dow Street, Dundee, DD1 5EH, UK

author email corresponding author email

BMC Developmental Biology 2008, 8:63doi:10.1186/1471-213X-8-63

Published: 9 June 2008

Additional files


Additional file 1:

Migration of cells from anterior and posterior primitive streak is shown, following labelling with DiI (red) in the anterior streak and DiO (green) in the posterior streak. Anterior cells do not migrate laterally but move into the paraxial mesoderm where they undergo convergent extension. Posterior cells migrate laterally before undergoing convergent extension movements. The image sequence shown in Fig 3A was generated from this movie.

Format: MOV Size: 7.6MB Download file

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