Table 3

genotype

Distribution of RGCs projecting ipsilaterally from each retinal quadrant (expressed as % of total projection to thalamus)

% of ipsilateral projection originating from vt retina


dn

dt

vn

vt


Pax6Sey/+

0.53 ± 0.26

0.23 ± 0.01

0.40 ± 0.20

1.44 ± 0.72

44 ± 25

Pax6+/+

0.22 ± 0.06

0.39 ± 0.12

0.33 ± 0.17

1.16 ± 0.47

45 ± 10

PAX77+

1.03 ± 0.46

1.59 ± 0.42

1.27 ± 0.43

4.01 ± 2.32

34 ± 11

PAX77+/+

1.24 ± 0.71

2.30 ± 1.57

0

5.84 ± 2.70

44 ± 18


Distributions of RGCs projecting ipsialterally to the thalamus in Pax6Sey/+, Pax6+/+, PAX77+, and PAX77+/+ embryos in the four retinal quadrants. Note that in all genotypes the ipsilaterally projecting RGCs are enriched in the ventrotemporal (vt) quadrant (shown in bold) compared to the dorsonasal (dn), ventronasal (vn), and dorsotemporal (dt) quadrants regardless of the overall size of the ipsilateral projection (shown in Fig 8 B,C). All values mean ± s.e.m. Sample sizes: Pax6Sey/+ n = 4; Pax6+/+ n = 9; PAX77+ n = 5; PAX77+/+ n = 4.

Manuel et al. BMC Developmental Biology 2008 8:59   doi:10.1186/1471-213X-8-59

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