Table 2

Transient BD has long-term survival benefits.

Cohort

Number of animals

Mean Survival After Transfer

Mean Control Fed Survival After Transfer

p-value


CF

57

-

20.5 ± 0.6

-

BD

97

34.8 ± 0.7

20.5 ± 0.6

1.7 × 10-19

Day 8 BD to CF

50

24.4 ± 0.9

20.5 ± 0.6

3.0 × 10-4

Day 14 BD to CF

36

28.3 ± 1.0

22.0 ± 0.6

2.0 × 10-6

Day 28 BD to CF

117

35.7 ± 0.4

31.4 ± 0.4

0.03


'Mean survival after transfer' is the average life span of animals in each group that were alive at the time the cohort was switched from BD back to a control fed (CF) diet. 'Mean control fed survival after transfer' is the average life span of control fed animals that were alive at the time the corresponding cohort was switched to BD. Survival data are shown as mean ± standard error. P-values were calculated by the Wilcoxon Rank-Sum test using the MATLAB 'ranksum' function. Bacterial deprivation (BD) was initiated at the 2nd day of adulthood.

Smith et al. BMC Developmental Biology 2008 8:49   doi:10.1186/1471-213X-8-49

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