Table 1

BD increases life span independent of the age at which it is initiated.

Cohort

Number of animals

Mean Survival After Transfer

Mean Control Fed Survival After Transfer

p-value


CF

30

-

23.6 ± 0.7

-

Day 4 BD

110

37.6 ± 0.5

23.6 ± 0.7

1.4 × 10-15

Day 8 BD

79

38.6 ± 0.5

23.6 ± 0.7

2.1 × 10-15

Day 14 BD

158

38.1 ± 0.4

23.6 ± 0.7

4.8 × 10-17

Day 20 BD

112

35.3 ± 0.7

25.0 ± 0.7

9.1 × 10-8

Day 24 BD

52

35.2 ± 0.8

29.7 ± 1.2

0.01


'Mean survival after transfer' is the average life span of animals in each group that were alive at the time the cohort was switched from control fed (CF) to bacterial deprivation (BD). 'Mean control fed survival after transfer' is the average life span of control fed animals that were alive at the time the corresponding cohort was switched to BD. Survival data are shown as mean ± standard error. P-values were calculated by the Wilcoxon Rank-Sum test using the MATLAB 'ranksum' function.

Smith et al. BMC Developmental Biology 2008 8:49   doi:10.1186/1471-213X-8-49

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