Table 2

Effects of mutations on the morphology of the pharyngeal NSM neurons.
Genotype
 Normal (%)
 Short dorsal process (%)
 Short sub-ventral process (%)
 Long dorsal process (%)
 Dorsal process absent (%)
 Sub-ventral process absent (%)
 Anterior guided axons (%)
 Absent Minor process (%)
 Others* (%)
 N
Controls
wild-type
 95
 4
 1





185
unc-30
 93
 4
3



1
 196
unc-46
 91
 6
 1
 1
 1



328
Growth cone-defective mutants
unc-14
 72
 11
 4
1


10
 202
unc-41
 96
 3
 1





172
unc-51
 23
 22
 16
29
 1
1
 9
 226
unc-73
 30
 20
 6
 4
 27
 10

3
 283
unc-76
 35
 37
 2
 1
 25


1
 272
unc-115
 87
 1
 2
 10



1
 225
unc-119
 29
 41
 4
 1
 22


4
 269
Positional cue and cue interpretation mutants.
fax-1
 84
 8
 6
 2




198
kal-1
 61
 10
 15
 1
 6
 5

2
 219
max-1
 95
 1
 1
 3




228
mob-20
 100







194
sax-3
 26
 1
 3
 2
 12
37
19
 210
slt-1
 41
 16
 22
 7
 4
 6

4
 247
smp-2
 64
 18
 6
 5
 5
 3


168
unc-5
 40
 26
 6
 3
 13
 11

1
 181
unc-6
 40
 24
 1
 2
 32


1
 307
unc-34
 9
 7
3
 77
 1
 1
3
 204
unc-40
 39
 3
 5
 12
 26
 8
 4
4
 229
unc-69
 26
 38
8
 28
 1


184
unc-129
 57
 15
 9
 7
 6
 6


198
vab-1
 87
 7
3
 1
 1

1
 181
vab-8
 95

2
 1


2
 214
wrk-1
 83
 10
 3
2
 2


189
zag-1
 83
 2
 4
 4
 5
 2

1
 200
zig-4
 92
4
 4




100
Extracellular matrix protein
mec-1
 75
4
 8
9

4
 253
sax-7
 32
 1
 4
 37
 7
 30

1
 145
sdn-1
 41
 11
 5
 4
 6
 32

1
 254
unc-23
 68
 3
 2
 5
 2
 1

20
 237
unc-52
 64
 8
 7
 3
 2


16
 213
unc-61
 75
 5
16
 3
 1


172
unc-112
 75
 6
 9
 7
 3
 1


340
Synapse Function mutants
syg-1
 43
 26
 1
24
 5

1
 183
unc-101
 0
 4
 2
 7
 3
 5
100
 13
 223
unc-104
 94
 5
 1





174
Genes important for proper function of NSM
mod-5
 73
 17
 7
3
 1


168
tph-1
 94
 1
 3
 2




168
Pharyngeal morphology mutants
mnm-5
 79
 2
1
 8
1
11
 267
pha-2
 4
 1
 1
21
45
27
 141

*The category "others" reflect specific phenotypes encountered for individual mutants, as follows:

mnm-5: misplaced cell bodies, complete loss of guidance.

pha-2: misplaced cell bodies; sub-branching of the misguided branches; minor process absent; multiple branching.

sax-3: thickened endings of axons; misplaced cell bodies; multiple branching; all branches are anterior misguided; sub-branching of the misguided branches; minor process absent.

unc-23: thickened endings of axons.

unc-51: milder defects similar to unc-73 (ectopic branching).

unc-52: thickened endings of axons.

unc-73: thickened endings of axons; multiple branching from cell bodies.

unc-101: thickened endings of axons; multiple branching from cell bodies.

Axäng et al. BMC Developmental Biology 2008 8:38   doi:10.1186/1471-213X-8-38