Table 1

Numbers and health status of pre-implantation embryos collected following chronic and acute maternal TCDD exposure

Treatment (# animals)

Average # embryos/animal (range)

Average # blastomere/embryo (range)

# Normal embryos/total embryos (%)

Chronic exposure (compaction)

Control (3)

13.0 (12–14)

12.5 (7–18)

31/39 (79.5)

50 ng/kg/wk TCDD (3)

13.7 (13–15)

11.3 (4–17)

15/41 (36.6)*

Acute exposure (compaction)

Control (3)

13.3 (13–14)

9.5 (3–16)

32/40 (80.0)

50 ng/kg TCDD (5)

12.0 (11–13)

9.5 (3–16)

31/60 (51.7)*

1 μg/kg TCDD (6)

9.2 (3–13)

10.1 (6–16)

21/46 (45.7)*

Acute exposure (blastocyst)

Control (6)

10.5 (9–12)

31.9 (13–52)

48/63 (76.2)

50 ng/kg TCDD (3)

9.7 (9–10)

32.1 (8–58)

17/29 (58.6)

1 μg/kg TCDD (5)

9.0 (9–12)

37.5 (8–63)

20/45 (45.5)*

*Significantly different from control

Hutt et al. BMC Developmental Biology 2008 8:1   doi:10.1186/1471-213X-8-1