Table 1

Human PKD can replace Drosophila PKD activity

UAS-Line

n

0/1

2

3


GFP-lacZ

19

0%

0%

100%

PKD-WT10-2

44

77,2%

4,6%

18,2%

PKD-SE139-2

35

94,3%

2,9%

2,8%

hPKD2II-3

22

63,6%

36,4%

0%

hPKD2X-2

16

89,0%

8,3%

2,7%

hPKD3V-1

28

79,6%

14,3%

6,1%

hPKD3X-1

21

86,5%

8,1%

5,4%

PKCi

23

0%

0%

100%


The given UAS-line was overexpressed along the antero-posterior border with help of the ptc-Gal4 driver line together with UAS-dsPKD6-4. As control, ptc > dsPKD6-4 was crossed to UAS-GFP-lacZ and wings used for comparison. Wings of at least ten flies were mounted and examined at high magnification. n, number of wings scored. 0/1, wild type looking wing; 2, weak phenotype; 3, phenotype indistinguishable from control. Numbers represent percentage of wings with given phenotype.

Maier et al. BMC Developmental Biology 2007 7:74   doi:10.1186/1471-213X-7-74

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