Table 2

Rescue of the mfr egg patterning defect phenotype by transgenes.

Strain

Female Genotype

n*

% Eggs Patterning Defects


control (mfr+)

w/w+; bw/SM1; st mfrZ1386/TM6 or w/w+; bw/SM1; st mfrZ0695/TM6

293

9%

control (mfr-)

w/w+; bw/SM1; st mfrZ1386/st mfrZ0695

269

40%Ω

transgenic A

w/w+; bw/P{w+mcmfr+t10.7}A;mfrZ1386/mfrZ0695

197

21%Ω

transgenic B

w/w+; bw/P{w+mcmfr+t10.7}B;mfrZ1386/mfrZ0695

220

21%Ω

transgenic A two copies

w; P{w+mcmfr+t10.7}A;mfrZ1386/mfrZ0695

320

11%


A and B are two independent insertions of the transgene

*number of eggs assayed

siblings of the control (mfr-) females that have either the mfrZ1386 or mfrZ0695 mutation balanced over TM6

Ωpercentage of defects is significantly different from control (mfr+) for control (mfr-)

P < 0.0001 R2 = 0.05; for transgenic A, P = 0.0002 R2 = 0.04; and for transgenic B, P = 0.0001 R2 = 0.04.

Smith and Wakimoto BMC Developmental Biology 2007 7:21   doi:10.1186/1471-213X-7-21

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