Table 2

Adult lifespan of age-1(mg109) dauer arrest suppressors.

Genotype

Adult Lifespan

Mean

SE

(n)

Log-Rank

Wildtype ^a

14.9

0.33

255

-

age-1(mg109) ^{a, b}

21

0.66

142

-

daf-16(mg242);age-1(mg109) ^a

9.0

0.11

225

<0.0001^g

daf-16(mg255);age-1(mg109) ^a

9.8

0.11

283

<0.0001^g

age-1(mg109);akt-1(mg247) ^a

25.5

0.42

205

<0.0001^{c, g}

age-1(mg109);pdk-1(mg261) ^a

20.2

0.69

166

<0.6941^{d, g}

age-1(mg109);mg227 ^a

30.5

0.38

279

<0.0001^g

Wildtype; control RNAi ^f

22.9

0.49

53

-

Wildtype; daf-16 RNAi ^f

16.4

0.26

107

-

age-1(mg109);mg227; daf-16 RNAi ^f

18.7

0.27

97

^a Lifespan assays performed at 25°C

^b These are homozygote progeny of age-1(mg109) homozygous hermaphrodites that have been maternally rescued for dauer arrest [27].

^c Although the akt-1(mg247) allele increased mean lifespan compared to age-1(mg109) control animals, the median lifespan and maximum lifespan was not significantly affected (age-1(mg109)^{a, b}, 25 days median, 32 days maximum; age-1(mg109);akt-1(mg247)^a, 24 days median, 33 days maximum, Figure 4)

^d Wilcoxan P value = 0.2370.

^f Lifespan assays performed at 20°C.

^g P vs age-1(mg109)^{a, b}

SE, Standard error.

n indicates the number of animals scored in at least three independent trials.

Gami et al. BMC Developmental Biology 2006 6:45   doi:10.1186/1471-213X-6-45