Tramtrack affects targets of the Notch pathway involved in the mitotic-to-endocycle transition. Ttk mutant clones past stage 6–7 mitotic-to-endocycle transition show upregulation of stg-lacZ (A, A'; arrow, red, s.10 egg chamber, stg 6.4 kb promoter construct, 37% n = 27) and dap-myc (B, B'; arrow, red, s.8 egg chamber, dacapo5gm promoter construct, 64% n = 25) and down-regulation of Fzr-lacZ (C, C'; red, s.9 egg chamber, fzrG0326, 70% n = 123). All cells are marked with DAPI (blue), GFP is green.
Jordan et al. BMC Developmental Biology 2006 6:16 doi:10.1186/1471-213X-6-16