Figure 2.

A family of proteins related to GDT1 and GDT2. 8 GDT proteins are shown schematically. SMART, TMHMM and MEMSAT programs were used for sequence analysis. The level of grey indicates the extent of conservation. SS – signal sequence, TM – transmembrane domain, R – repetitive polyAsn-containing sequences, IN – predicted cytoplasmic domains, OUT – predicted lumenal/extracellular domains. The putative kinase domains are marked with "+" if they appear to be functional or with "-" if they are degenerate.