Figure 4.

Edema in Ptdsr^-/- mice (a) The Ptdsr^-/- mutant (15.5 dpc) is growth retarded and the severe edema along the back of the embryo is visible. (b, c) Sagital sections of embryos at 16.5 dpc. The mutant embryo (c) exhibits massive subcutaneous edema compared to a wild-type (b) littermate. Scale bar = 100 μm in (b) and (c).