Volumetric and segmentation based renderings of adult normal and acetaminophen intoxicated livers. (a) Volumetric rendering of normal adult human liver optimized for CK19 presentation. (b-d) Segmentation based renderings depicting the progression of the portal vessels and the distribution of CK19. (e) Volumetric rendering of acetaminophen intoxicated liver with clear presentation of the CK19 positive ductular reaction. (f-h) Segmentation of CK19 from the same volume as (e) illustrating the complex regenerative network. (a, e) CK19 is immunostained in brown color. (b-d and f-h) CK19 is presented in black and portal vessels in white colors. Arrows point to the hepatic artery. PV = Portal vein.
Vestentoft et al. BMC Developmental Biology 2011 11:56 doi:10.1186/1471-213X-11-56