Table 2

Summary of the growth dynamics of EDL myofibres

Age (days)

P3

P7

P14

P21

P56


Myofibre length (μm)

1104.5

±43.8 (20)

2688.6*

±66.0 (31)

3663.0*

±57.8 (36)

4069.8*

±70.7 (42)

4977.8*

±83.9 (31)


Sarcomere length (μm)

-

2.16

±0.08 (764)

-

2.15

±0.07 (947)

2.16

±0.07 (969)


Myonuclei per myofibre

51.9

±1.4 (71)

102.8*

±2.0 (61)

206.7*

±2.4 (204)

244.5*

±3.5 (111)

256.1

±4.7 (78)


Myonuclei per Unit length(100 μm)

4.7

3.7

5.6

6

5.1


Satellite cells per myofibre

-

14.3

±0.7 (61)

9.4*

±0.4 (204)

4.5*

±0.3 (111)

5.8

±0.3 (78)


Data are mean ± SEM (n: number of myofibres) from 3 × 3F-nlacZ-E mice per age for length measurements and at least 3 each of Myf5nlacZ/+ and 3F-nlacZ-E mice per age for myonuclear and satellite cells counts. For sarcomere length, data are mean ± SEM (n: number of sarcomeres) from three mice at each age. Asterisk indicates significant difference from preceding value (ANOVA with Tukey HSD post-hoc testing; p < 0.01).

White et al. BMC Developmental Biology 2010 10:21   doi:10.1186/1471-213X-10-21

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