Comparision between the predicted effects of miRNAs and their expression as determined by RT-PCR. The estimated copy number (Log(initial template)) of each miRNA in a given sample is plotted against the probability (Wilcoxon ranked sum test) that it is having an effect upon target gene expression. The most highly expressed miRNAs have very significant effects upon predicted target gene expression and the overall correlation between miRNA expression and significance of effect upon target gene expression is significant (p = 4.0E-04; Spearman rank correlation).
Arora et al. BMC Developmental Biology 2010 10:1 doi:10.1186/1471-213X-10-1