Specific expression of EYFP in R26R-EYFP mice carrying Isl1-Cre. A, transverse section of an E14.5 R26R-EYFP/+; Isl1-Cre/+ embryo, revealing expression of EYFP in the motor neurons and dorsal root ganglia. The apparent expression in surface ectoderm is an artifact, as it was also seen in non-transgenic embryos (data not shown). Panel B, transverse section of E12.5 R26R-lacZ; Isl1-Cre embryo, showing a comparable pattern of β-gal staining.
Srinivas et al. BMC Developmental Biology 2001 1:4 doi:10.1186/1471-213X-1-4