BMC Developmental Biology
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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good PhD
Welcome to BMC Developmental Biology published by BioMed Central
BMC Developmental Biology is an open access journal publishing original peer-reviewed research articles in the development, growth, differentiation and regeneration of multicellular organisms, including molecular, cellular, tissue, organ and whole organism research.
BMC Developmental Biology (ISSN 1471-213X) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Zoological Record, Current Contents, Thomson Reuters (ISI) and Google Scholar.
BMC Developmental Biology 2009, 9 :56
A web-accessible database of genes that are expressed in the CNS midline lineage during Drosophila embryogenesis integrates expression data with the ability to identify individual cell types and will facilitate studies of neuronal and glial development.
BMC Developmental Biology 2009, 9 :53
A loss-of-function ras allele (rasKP) causes excessive apoptosis in the Drosophila eye via activation of JNK and, to a lesser extent, Hid, with cell and organ size also affected in the wing.
BMC Developmental Biology 2009, 9 :45
Expression of the transcription factor Yin Yang 2 (YY2) in the cerebellum and neocortex of mice varies during embryonic and postnatal development, suggesting a functional role of YY2 in brain development.
Image highlight
Undersized eye of zebrafish embryo with a mutated condensin gene. [more ]
more info ]
Research article
Progenitor cells of the rod-free area centralis originate in the anterior dorsal optic vesicle Sae Kyung Shin, Keely M Bumsted O'Brien BMC Developmental Biology 2009, 9 :57 (25 [Abstract ] [Provisional PDF ]
Database
MidExDB: A database of Drosophila CNS midline cell gene expression Scott R Wheeler, Stephanie B Stagg, Stephen T Crews BMC Developmental Biology 2009, 9 :56 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Wnt4 is not sufficient to induce lobuloalveolar mammary development Young Chul Kim, Rod J Clark, Francisco Pelegri, Caroline M Alexander BMC Developmental Biology 2009, 9 :55 (30 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development Ita Costello, Christine A Biondi, Jennifer M Taylor, Elizabeth K Bikoff, Elizabeth J Robertson BMC Developmental Biology 2009, 9 :54 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophila eye Yue Wu, Yuan Zhuang, Min Han, Tian Xu, Kejing Deng BMC Developmental Biology 2009, 9 :53 (20 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Expanded progenitor populations, vitreo-retinal abnormalities, and Mleprechaun/patched 2 retina Jonathan Bibliowicz, Jeffrey M Gross BMC Developmental Biology 2009, 9 :52 (19 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
A tamoxifen inducible knock-in allele for investigation of E2A function Mary E Jones, Motonari Kondo, Yuan Zhuang BMC Developmental Biology 2009, 9 :51 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells Jingxian Zhang, Robert J Lipinski, Jerry J Gipp, Aubie K Shaw, Wade Bushman BMC Developmental Biology 2009, 9 :50 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Use of KikGR a photoconvertible green-to-red fluorescent protein for cell labeling and lineage analysis in ES cells and mouse embryos Sonja Nowotschin, Anna-Katerina Hadjantonakis BMC Developmental Biology 2009, 9 :49 (9 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Muscle differentiation in a colonial ascidian: organisation, gene expression and evolutionary considerations Valentina Degasperi, Fabio Gasparini, Sebastian M Shimeld, Chiara Sinigaglia, Paolo Burighel, Lucia Manni BMC Developmental Biology 2009, 9 :48 (8 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Review
Action potential evoked transmitter release in central synapses: insights from the developing calyx of Held Lu-Yang Wang, Michael J Fedchyshyn, Yi-Mei Yang Molecular Brain 2009, 2 :36 (25 [Abstract ] [Provisional PDF ]
Research
PDGF-Ralpha gene expression predicts proliferation, but PDGF-A suppresses transdifferentiation of neonatal mouse lung myofibroblasts Patricia W Kimani, Amey J Holmes, Ruth E Grossmann, Stephen E McGowan Respiratory Research 2009, 10 :119 (25 [Abstract ] [Provisional PDF ]
Research
Ets-2 and p53 mediate cAMP-induced MMP-2 expression, activity and trophoblast invasion Elsebeth Staun-Ram, Shlomit Goldman, Eliezer Shalev Reproductive Biology and Endocrinology 2009, 7 :135 (25 [Abstract ] [Provisional PDF ]
Research
Fhl5/Act, a CREM-binding transcriptional activator required for normal sperm maturation and morphology, is not essential for testicular gene expression Aurelie Lardenois, Frederic Chalmel, Philippe Demougin, Noora Kotaja, Paolo Sassone-Corsi, Michael Primig Reproductive Biology and Endocrinology 2009, 7 :133 (24 [Abstract ] [Provisional PDF ]
Research
Developmental expression of a functional TASK-1 2P domain K+ channel in embryonic chick heart Hengtao Zhang, Jeremy Parker, Neal Shepherd, Tony L Creazzo Journal of Biomedical Science 2009, 16 :104 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Novel motifs distinguish multiple homologues of Polycomb in vertebrates: expansion and diversification of the epigenetic toolkit Ramamoorthy Senthilkumar, Rakesh K Mishra BMC Genomics 2009, 10 :549 (20 [Abstract ] [Provisional PDF ]
Research article
Expression profiling of rainbow trout testis development identifies evolutionary conserved genes involved in spermatogenesis Antoine D Rolland, Jean-Jacques Lareyre, Anne-Sophie Goupil, Jerome Monfort, Marie-Jose Ricordel, Diane Esquerre, Karine Hugot, Remi Houlgatte, Frederic Chalmel, Florence F Le Gac BMC Genomics 2009, 10 :546 (20 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Short Report
Zebrafish aplnra functions in epiboly Svanhild Nornes, Ben Tucker, Michael Lardelli BMC Research Notes 2009, 2 :231 (19 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
In vivo imaging of the tonoplast intrinsic protein family in Arabidopsis roots Stefano Gattolin, Mathias Sorieul, Paul R Hunter, Roman H Khonsari, Lorenzo Frigerio BMC Plant Biology 2009, 9 :133 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Review
Novel insights into the differential functions of Notch ligands
in vascular formation
Tsutomu Kume Journal of Angiogenesis Research 2009, 1 :8 (16 [Abstract ] [Provisional PDF ]
Featured articles
ller glial reactivity in the zebrafish leprechaun/patched2 retina