Additional file 9.

Formation of lamellipodia and filopodia on micro-patterned surfaces. Lamellipodia but not filopodia are dependent on an adhesive surface. A. Cells were spread on 5 μm fibronectin and BSA stripes for 60 minutes. Scale bar 10 μm B. Cells were spread on 10 μm fibronectin and BSA stripes for 60 minutes. Scale bar 10 μm. Hollow arrows indicate filopodia. Solid arrows indicate lamellipodia/ruffles. Actin was labelled with Alexa 350 phalloidin. Scale bar 10 μm.

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Johnston et al. BMC Cell Biology 2008 9:65   doi:10.1186/1471-2121-9-65