Static cell adhesion assays on uniformly coated substrates. Different cell-cell adhesion molecules were used to evaluate cell adhesion of C2C12 mouse myoblasts (A) and SHSY-5Y human neuroblastoma cells (B). Values for adhesion to Laminin, a well-known component of cell matrix, were set to one relative unit. Agrin C100 functions as an adhesion molecule within the same range as Laminin, Cadherins, and Immunoglobulin superfamily members. Values are averages of three independent trial ± S.D.
Wolfram et al. BMC Cell Biology 2008 9:64 doi:10.1186/1471-2121-9-64