Figure 1.

Prostaglandin E2 treatment causes a differential redistribution of the AJC proteins. Caco-2 cells were grown on sterile glass coverslips and after PGE2 treatments they were processed for immunofluorescence analysis using specific antibodies of AJC proteins, as indicated. Images show control (0 min) and treated for 15, 30 and 60 min treatments with 1 μM PGE2. Note that – with the exception of ZO-1 – E-cadherin, β-catenin, claudin-1 and occludin showed alterations of the staining pattern at 15 and 30 min of treatment. An apparent recovery of the labeling was observed at 60 min for E-cadherin, β-catenin and claudin-1, but not for occludin that showed membranous projections to the cytoplasm. Bar: 10 μm

Tanaka et al. BMC Cell Biology 2008 9:63   doi:10.1186/1471-2121-9-63
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