Table 1

Expression of genes encoding LPS receptor and signaling molecules in osteoblastic cells

Cell type

TLR2

TLR4

MD2

CD14

MyD88

References


SaOS-2, HOS, MG-63

-

+a

+

+

+

[46]

MC3T3-E1

+

+

NA

NA

NA

[40]

ST-2

+

+

NA

NA

NA

[40]

SaM-1 cell

NA

NA

NA

+

NA

[47]

Primary mouse

+

+

NA

+

NA

[48]

osteoblasts from

+

+

NA

NA

NA

[40]

embryonic calvaria

NA

NA

NA

+

NA

[49]


+, constitutively expressed; -, not detected; NA, not available.

SaOS-2, HOS, MG-63: human osteosarcoma cell-lines; MC3T3-E1: mouse osteoblastic cell-line; ST-2: mouse stromal cell-line; SaM-1: human osteoblastic cell-line from periosteum

TLR2: Toll-like receptor 2; TLR4: Toll-like receptor 4.

a Protein expression of TLR4 was also observed for SaOS-2 only.

Mo et al. BMC Cell Biology 2008 9:52   doi:10.1186/1471-2121-9-52

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