Table 1

Expression patterns of FUS, EWS and TAF15 in human tissues by TMA immunohistochemistry analysis

FUS

EWS

TAF15

Organ

Tissue/Cell type

Nuclear

Cytoplasmic

Nuclear

Cytoplasmic

Nuclear

Cytoplasmic


Adrenal gland

Parenchymal cells

+++

+++

+++

-

+++

+++

Appendix

Appendix smooth muscle

+++

+++

+++

-

+++

+++

Brain

- white matter

Glial cells

+++

-

+++

-

+++

-

- grey matter

Neurons

+++

+

+++

-

+++

+

Breast

Glandular epithelium

+++

+++

+++

-

+++

+++

Myoepithelial cells

+++

+++

++

-

+++

+++

Endothelium, capillaries

+++

++

+++

-

+++

+++

Adipocytes

+++

-

+++

-

+++

-

Colon & Rectum

Surface epithelium

+++

+++

++

-

+++

+++

Crypt epithelium

+++

+++

++

-

+++

+++

Malt tissue, germinal centre

+++

-

+++

-

+++

-

Malt tissue, mantle zone

+++

-

+++

-

++

-

Duodenum

Enterocytes, villus epithelium

+++

+++

++

-

+++

+++

Enterocytes, crypt epithelium

+++

+++

++

-

+++

+++

Ganglion cells

+++

+++

+++

-

+++

+++

Endometrium

- proliferative

Glandular epithelium

+++

+++

+++

-

+++

+++

Stromal cells

+++

-

++

-

+++

-

- secretory

Glandular epithelium

+++

+++

+++

-

+++

+++

Stromal cells

++

-

++

-

++

-

Esophagus

Squamous epithelium, suprabasal

+++

+++

+++

-

+++

+++

Squamous epithelium, basal

++

+++

+

-

++

+++

Endothelium, medium-sized arteries

+++

+

+++

-

+++

++

Smooth muscle cells

+++

+++

+++

-

+++

+++

Gallbladder

Mucosal epithelium

+++

+++

+++

+++

+++

+++

Smooth muscle cells

+++

+++

+++

-

+++

+++

Heart

Cardiac muscle cells

-

-

-

-

-

-

Cardiac endothelium

-

-

++

-

-

-

Kidney

Glomeruli

++

-

++

-

++

-

Proximal tubuli

+++

+++

+++

+++

+++

+++

Distal tubuli

+++

+++

+++

+++

+++

+++

Liver

Hepatocytes

-

+++

++

+++

-

+++

Bile duct epithelium

+++

+++

+++

+++

+++

+++

Lung & Bronchus

Respiratory epithelium

+++

+++

+++

-

+++

+++

Glandular epithelium

+++

+++

+++

-

+++

+++

Pneumocytes

++

-

++

-

++

+

Chondrocytes

+++

-

++

-

++

-

Endothelium, capillaries

+++

-

+++

-

+++

-

Muscle artery, endothelial cells

+++

-

+++

-

+++

-

Muscle artery, smooth muscle

+++

+++

+++

-

+++

+++

Lymph node

Germinal centre

++

-

++

-

++

-

Mantle zone

++

-

++

-

++

-

Myometrium

Smooth muscle cells

+

-

+

-

+

-

Nasal mucosa

Respiratory epithelium

+++

++

++

-

+++

++

Glandular epithelium

+++

+++

+++

-

+++

+++

Ovary

Follicular epithelium

+++

+++

++

-

+++

+++

Ovarial stromal cells

+++

-

+++

-

+++

-

Pancreas

Exocrine glands

+++

+++

+++

-

+++

+++

Duct epithelium

+++

+++

+++

-

+++

+++

Endocrine cells

+++

+++

+++

+++

+++

+++

Placenta

Syncytiotrophoblasts

++

++

+

+

++

+++

Cytotrophoblasts

+++

+

++

+

+++

+

Prostate

Prostate epithelium

+

+

++

+

++

+

Basal cells

+++

-

+++

-

++

-

Salivary gland

Serous cells

+++

+++

+++

++

+++

+++

Mucous cells

+++

+

++

-

+++

+

Intercalated/striated ducts

+++

+++

+++

+++

+++

+++

Myoepithelium

+++

-

+++

-

+++

-

Salpinx

Glandular epithelium

+++

+++

+++

-

+++

+++

Seminal vesicle

Epithelium

+++

+++

+++

+++

+++

+++

Skeletal muscle

Skeletal muscle fibers

++

-

++

-

+++

-

Skin & Subcutis

Keratinocytes

+++

+++

+++

-

+++

+++

Melanocytes

-

-

-

-

-

-

Fibroblasts

+++

-

+++

-

+++

-

Ecrine epithelium, sweat gland

+++

+++

++

-

+++

+++

Endothelium, capillaries

+++

-

+++

-

+++

-

Adipocytes

+++

-

++

-

++

-

Spleen

Lymphocytes, red and white pulp

++

-

++

-

+

-

Stomach

- body

Surface & foveolar epithelium

+++

+++

+++

-

+++

+++

Specialized glandular epithelium

+

+++

+

+++

+

+++

- antrum

Surface & foveolar epithelium

+++

+++

++

-

+++

+++

Specialized glandular epithelium

+++

+++

++

-

+++

++

- smooth muscle

Smooth muscle cells

+++

-

+++

-

+++

-

Small bowel

Enterocytes, villus epithelium

+++

+++

++

-

+++

+++

Enterocytes, crypt epithelium

+++

+++

++

-

+++

+++

Ganglion cells

+++

+++

+++

+++

+++

+++

Testis

Germinal epithelium

+++

-

+++

-

+++

-

Leydig intestitial cells

++

++

++

-

++

+++

Spermatides

+

-

+

-

++

-

Thymus

T-lymphocytes

++

-

++

-

++

-

Epithelium

+++

+

+++

-

+++

+++

Thyroid

Follicular epithelium

+++

+++

++

-

+++

+++

Tonsil

Squamous cell epithelium

+++

+++

+++

-

+++

+++

Lymphocytes

+++

-

+++

-

+++

-

Umbilical cord

Stromal cells

+++

++

++

-

+++

++

Urinary bladder

Urothelium

+++

+++

+++

-

+++

+++

Uterine cervix

Squamous epithelium, basal

+++

+++

++

-

+++

+++

Squamous epithelium, suprabasal

+++

+++

+++

-

+++

+++


The percentage of FET positive cells within an organ is indicated as: +++ (100-76% positively staining cells), ++ (75-26% positively staining cells), + (25-1% positively staining cells) and - (negative).

Andersson et al. BMC Cell Biology 2008 9:37   doi:10.1186/1471-2121-9-37

Open Data