Table 1

Proteins identified in lamellar bodies with MALDI-TOF MS

Protein identified
NCBI accession #
Peptide matched
Sequence covered %
Mascot Score
Molecular mass

Ca2+-binding proteins





Annexin A1
P07150
16
42
137
38674
Annexin A2
Q07936
16
49
129
38523
Annexin A3
LURT3
15
45
148
36341
Annexin A4
Q5U362
14
42
140
35871
Annexin A5
P14668
18
52
156
35591
Annexin A6
P48037
14
20
66
75575
Annexin A7
Q6IRJ7
8
17
57
49987
Calreticulin precursor
AAH62395
12
24
119
47966






Structural proteins





Actin-beta
ATRTC
10
31
97
41724
Vimentin
P31000
20
38
119
53569
Myosin-9 (Nonmuscle myosin heavy chain IIa)
Q62812
47
24
143
226066
Tropomyosin 1
AAA42289
10
32
60
32938
Moesin (Membrane-organizing extension spike protein)
O35763
16
20
64
67566
Cytokeratin 19
AAR36876
15
38
108
44609






Surfactant-related proteins





Surfactant protein A precursor
P08427
10
43
63
26272
Surfactant protein B
Q6IN44
7
19
62
41590
ABCA3
AAH88202
7

160
240735
Peroxiredoxin-6
NP_446028
8
33
78
24672
Apolipoprotein A-I precursor
AAH89820
10
35
84
30043
Apolipoprotein A-IV
AAH91159
16
39
122
44429
Lysosome membrane protein II
P27615
8
16
52
53925






Ion channels





H+-transporting two-sector ATPase alpha chain precursor
J05266
12
29
57
58790
F1-ATPase beta chain
1MABB
10
32
83
49043
Unnamed protein product
CAF05438
20
14
113
146309






Membrane traffic





EHD1
AAH82030
11
20
65
60565






Protein processing





Serpinh1 protein
Q5RJR9
7
18
56
46532
Dipeptidyl peptidase IV membrane-bound form precursor
A39914
15
20
85
90869
Alpha-1-antitrypsin precursor
AAA40788
10
24
87
45807






Signal transduction





Mitogen-activated protein kinase kinase 1 interacting protein 1
AAH86353
6
57
65
13571
Rho GDP dissociation inhibitor (GDI) alpha
Q5XI73
7
36
90
23393
Rho-associated kinase beta
AAB37571
24
18
71
159527






Miscellaneous proteins





Albumin precursor
P02770
17
30
128
68674
Poly-ubiquitin
Q63654
5
44
82
11234
Complement C3 precursor
625256
13
7
61
186342
Heme-binding 23 K protein (HBP23)
1QQ2A
7
28
58
22095
Putative alpha (1,3) fucosyltransferase
CAC81972
10
19
59
42931
Periaxin
I58157
19
13
102
146948
Carbonic anhydrase IV
AAH97329
10
25
72
35054
Heat shock 70 kDa protein 5
AAH62017
19
33
95
72302
Protein disulfide isomerase associated 3
AAH62393
16
32
95
56588
Transferrin
AAP97736
14
19
80
76346
Ferroxidase precursor
A35210
11
9
122
120588
RSB-11-77 protein
NP_872610
12
28
75
42058
Cytochrome b5
AAB67609
13
27
78
11400

Wang et al. BMC Cell Biology 2008 9:34   doi:10.1186/1471-2121-9-34