Table 1

Proteins identified in lamellar bodies with MALDI-TOF MS

Protein identified

NCBI accession #

Peptide matched

Sequence covered %

Mascot Score

Molecular mass


Ca2+-binding proteins

Annexin A1

P07150

16

42

137

38674

Annexin A2

Q07936

16

49

129

38523

Annexin A3

LURT3

15

45

148

36341

Annexin A4

Q5U362

14

42

140

35871

Annexin A5

P14668

18

52

156

35591

Annexin A6

P48037

14

20

66

75575

Annexin A7

Q6IRJ7

8

17

57

49987

Calreticulin precursor

AAH62395

12

24

119

47966

Structural proteins

Actin-beta

ATRTC

10

31

97

41724

Vimentin

P31000

20

38

119

53569

Myosin-9 (Nonmuscle myosin heavy chain IIa)

Q62812

47

24

143

226066

Tropomyosin 1

AAA42289

10

32

60

32938

Moesin (Membrane-organizing extension spike protein)

O35763

16

20

64

67566

Cytokeratin 19

AAR36876

15

38

108

44609

Surfactant-related proteins

Surfactant protein A precursor

P08427

10

43

63

26272

Surfactant protein B

Q6IN44

7

19

62

41590

ABCA3

AAH88202

7

160

240735

Peroxiredoxin-6

NP_446028

8

33

78

24672

Apolipoprotein A-I precursor

AAH89820

10

35

84

30043

Apolipoprotein A-IV

AAH91159

16

39

122

44429

Lysosome membrane protein II

P27615

8

16

52

53925

Ion channels

H+-transporting two-sector ATPase alpha chain precursor

J05266

12

29

57

58790

F1-ATPase beta chain

1MABB

10

32

83

49043

Unnamed protein product

CAF05438

20

14

113

146309

Membrane traffic

EHD1

AAH82030

11

20

65

60565

Protein processing

Serpinh1 protein

Q5RJR9

7

18

56

46532

Dipeptidyl peptidase IV membrane-bound form precursor

A39914

15

20

85

90869

Alpha-1-antitrypsin precursor

AAA40788

10

24

87

45807

Signal transduction

Mitogen-activated protein kinase kinase 1 interacting protein 1

AAH86353

6

57

65

13571

Rho GDP dissociation inhibitor (GDI) alpha

Q5XI73

7

36

90

23393

Rho-associated kinase beta

AAB37571

24

18

71

159527

Miscellaneous proteins

Albumin precursor

P02770

17

30

128

68674

Poly-ubiquitin

Q63654

5

44

82

11234

Complement C3 precursor

625256

13

7

61

186342

Heme-binding 23 K protein (HBP23)

1QQ2A

7

28

58

22095

Putative alpha (1,3) fucosyltransferase

CAC81972

10

19

59

42931

Periaxin

I58157

19

13

102

146948

Carbonic anhydrase IV

AAH97329

10

25

72

35054

Heat shock 70 kDa protein 5

AAH62017

19

33

95

72302

Protein disulfide isomerase associated 3

AAH62393

16

32

95

56588

Transferrin

AAP97736

14

19

80

76346

Ferroxidase precursor

A35210

11

9

122

120588

RSB-11-77 protein

NP_872610

12

28

75

42058

Cytochrome b5

AAB67609

13

27

78

11400


Wang et al. BMC Cell Biology 2008 9:34   doi:10.1186/1471-2121-9-34

Open Data