Table 1

MT Array Morphology in Interphase Cells

Cell-type

Radial MT

Comet-Tail MT

Comets (%)


AX-2 Control

588

19

3.1%

380 K

60

279

82.3%

kif8-

461

1

0%

kif8-/380 K

451

0

0%

kif10-

583

12

2.0%

kif10-/380 K

475

23

4.6%

kif11-

212

26

10.9%

kif11-/380 K

127

84

39.8%

kif4-

189

9

4%

kif4-/380 K

68

84

55%


Numbers represent individual fixed cells, either containing a normal, radial interphase microtubule array (Radial MT), or a mutant comet-like microtubule array (Comet-Tail MT) resulting from dynein motor overexpression (380 K) in different control or kinesin null cell stains. % Comet refers to the percentage of total cells that showed the distinctive mutant phenotype.

Nag et al. BMC Cell Biology 2008 9:21   doi:10.1186/1471-2121-9-21

Open Data