Xenopus importin beta shows close homology to human importin beta. The protein sequence of Xenopus importin beta shows very close homology to human importin beta with 94% identities (828/876, black boxes) and 97% positives (857/876 gray and black boxes). The amino acid composition, along with the length of the protein, is well conserved between Xenopus and human importin beta. Three of the conservative amino acid differences between the Xenopus and human importin beta sequence are at residues involved in FG-domain binding (F217Y [82–84], I265V , and L505V ).
Delmar et al. BMC Cell Biology 2008 9:14 doi:10.1186/1471-2121-9-14