Effects of BIO on expression of adipogenic and osteogenic genes. hMADS3 cells were induced to undergo differentiation into adipocytes (left panel) or osteoblasts (right panel) in the presence of 0.5 μM BIO or 0.5 μM MeBIO. Ten days later, RNAs were prepared and expression of adipogenic or osteogenic markers was checked by qPCR. Results are the log2 inductions of BIO treated cells versus MeBIO treated cells. Expression data are colour-coded according to the scale.
Zaragosi et al. BMC Cell Biology 2008 9:11 doi:10.1186/1471-2121-9-11