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This article is part of the supplement: 2006 International Workshop on Multiscale Biological Imaging, Data Mining and Informatics

Open Access Research

Random subwindows and extremely randomized trees for image classification in cell biology

Raphaël Marée12*, Pierre Geurts2 and Louis Wehenkel2

Author Affiliations

1 GIGA Bioinformatics Platform, University of Liege, B34 Avenue de l'Hopital 1, Liege, 4000, Belgium

2 Bioinformatics and Modeling, Department of Electrical Engineering and Computer Science & GIGA Research, University of Liege, B28 Grande Traverse 10, Liege, 4000, Belgium

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BMC Cell Biology 2007, 8(Suppl 1):S2  doi:10.1186/1471-2121-8-S1-S2

Published: 10 July 2007



With the improvements in biosensors and high-throughput image acquisition technologies, life science laboratories are able to perform an increasing number of experiments that involve the generation of a large amount of images at different imaging modalities/scales. It stresses the need for computer vision methods that automate image classification tasks.


We illustrate the potential of our image classification method in cell biology by evaluating it on four datasets of images related to protein distributions or subcellular localizations, and red-blood cell shapes. Accuracy results are quite good without any specific pre-processing neither domain knowledge incorporation. The method is implemented in Java and available upon request for evaluation and research purpose.


Our method is directly applicable to any image classification problems. We foresee the use of this automatic approach as a baseline method and first try on various biological image classification problems.