Nature of the enlarged compartment in MCOLN1 RNAi clones. Confocal images of RAW264.7 and LS9 cells whose terminal compartments were pre-loaded with Dextran-Rhodamine (red) and stained for the indicated markers (green). All of the makers were detected using immuno-specific antibodies, except for GFP-Rab7 that was transfected into wild type and MCOLN1- cells. Bar is 5 μm.
Thompson et al. BMC Cell Biology 2007 8:54 doi:10.1186/1471-2121-8-54