Figure 5.

In vitro flow assays. Whole blood from WT (A) or HS1-/- (B) mice was flowed over collagen at a shear rate of 1000 s-1 for 4 min. Aggregates were fixed in formalin and imaged using DIC. Flow experiments were also carried out with DiOC6 labeled platelets (representative image shown in C) and the mean surface area of aggregates was calculated from fluorescence images (D). Means ± SEM are plotted (n = 3). No significant difference was observed between surface area coverage of WT and HS1-/- platelets (P = 0.669). Scale bars = 20 μM

Thomas et al. BMC Cell Biology 2007 8:46   doi:10.1186/1471-2121-8-46
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