Integrin ανß5 mediates MSC migration to WISP3 but not to CYR61. Integrin ανß5 mediates MSC migration to WISP3/CCN6 but not to CYR61/CCN1-protein. Results are presented as absolute numbers of migrated cells from three independent experiments measured in quadruplicate each (mean ± SD). MSCs were partly preincubated for 1 h with 50 μg/ml ανß3 (LM609) or ανß5 (P1F6) antibody (Ab) as indicated. CYR61 and WISP3 were used at a concentration of 2 μg/ml each.
Schütze et al. BMC Cell Biology 2007 8:45 doi:10.1186/1471-2121-8-45