Figure 1.

Alignment of human 14-3-3 with four isoforms of Hydra 14-3-3. Full length clones of 14-3-3 HyA and 14-3-3 HyB isoforms were described previously [18]. 14-3-3 HyC and 14-3-3 HyD were identified in expressed sequence tags from Hydra at NCBI. Helices 1-9 are indicated. Conserved amino acids that have been shown in the crystal structure to constitute the binding groove for target proteins are indicated with asterisks (basic face of the groove) and circles (hydrophobic surface) above the sequence (information from [24]). Alignments were made with the program GeneJockeyII (under MacOS9)

Pauly et al. BMC Cell Biology 2007 8:31   doi:10.1186/1471-2121-8-31
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