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Open Access Open Badges Research article

Dynamics of adipogenic promoter DNA methylation during clonal culture of human adipose stem cells to senescence

Agate Noer, Andrew C Boquest and Philippe Collas*

Author Affiliations

Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, PO Box 1112 Blindern, 0317 Oslo, Norway

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BMC Cell Biology 2007, 8:18  doi:10.1186/1471-2121-8-18

Published: 29 May 2007

Additional files

Additional file 1:

Supplementary Figures with legends. The data provided show DNA methylation profiles for adipogenic gene promoters in undifferentiated P4 and senescent ASCs (Supplementary Figure 1), and after three weeks of adipogenic differentiation at P4 and upon senescence (Supplementary Figure 2). Supplementary Figure 3 provides sequencing evidence for a C:T substitution in the LEP promoter.

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