Table 2

Homologous genes across mammalian species share a high degree of identity at the DNA level.

Percent identity between paired alignments

# identical 21 base pair stretches in paired alignments

# nucleotides compared


P-H

P-M

P-R

P-H

P-M

P-R

P

H

M

R


MCAK FL

66.4

62.1

58.6

3

1

2

2187

2178

2166

2016

Eg5 (18–346)

86.6

85.0

84.1

8

4

5

990

990

990

990

Kif2a FL

88.9

80.9

75.6

27

18

15

2040

2040

2151

2316

KifC1 (518–768)

78.4

78.8

78.2

1

2

1

760

754

754

760

Kif18a (110–383)

83.1

80.0

79.7

3

2

2

824

824

824

425

NFYB (64–200)

86.5

83.5

82.3

2

0

0

413

413

413

413

RPLP0 (49–165)

89.8

88.1

87.0

4

1

2

353

353

353

353


P, Potorous tridactylus sequence; H, Homo sapiens sequence; M, Mus musculus sequence; R, Rattus norvegicus sequence. MCAK and Kif2a are kinesin-13 family members; Eg5 is a kinesin-5 family member; KifC1 (HSET) is a kinesin-14 family member; Kif18a is a kinesin-8 family member; NFYB is a histone-like protein analogous to H2B; RPLP0 is ribosomal protein, large, PO. FL, full-length protein. Accession numbers can be found in Table 3.

Stout et al. BMC Cell Biology 2006 7:26   doi:10.1186/1471-2121-7-26

Open Data