Figure 11.

Proposed Receptor Ck – dependent signaling pathway involved in hTERT gene regulation at the transcriptional level. [LDL-low density lipoproteins; C-cholesterol moiety; RCk-Receptor Ck; PC-phosphatidylcholine; PLD-phospholipase D; PA-phosphatidic acid; DAGK-diacylglycerol kinase; PAP-phosphatidic acid phosphohydrolase; DAG-diacylglycerol; PKC-protein kinase C; PPARγ-peroxisome proliferator activated receptor γ; NF-κB-nuclear factor -κB; hTERT-human telomerase reverse transcriptase; T-transcription; LDLR-low density lipoprotein receptor; ApoB-apolipoprotein B; EGTA-ethyleneglycol-bis-(β-aminoethylether)-N,N,N',N'-tetraacetic acid; AbRCk-antibody against Receptor Ck; 25OH-C -25hydroxycholesterol; PROP-propranolol; PMA-phorbol 12-myristate 13-acetate; PIO-pioglitazone]

Sikand et al. BMC Cell Biology 2006 7:2   doi:10.1186/1471-2121-7-2
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