Table 2

Sequence identity matrix for the four different Shroom proteins which have been characterised experimentally.

Shrooma

1

2

3

4a


1

100/NA/100/100b

11.7/NA/32.9/37.7

10.9/NA/29.8/32.9

9.5/NA/NA/35.3

2

100/100/100/100

25.4/67.5/44.6/68.2

20.1/61.0/NA/65.8

3

100/100/100/100

15.9/63.6/NA/61.6

4a

100/100/NA/100


a This table makes use of the new nomenclature presented in Table 1. To avoid evolution-based dissimilarity, the human homologues have been used in the analysis. b Percent sequence identity is given in the format global/PDZ/ASD1/ASD2; NA, not applicable. Global sequence identity is based on those residues aligning to hShroom1 residues 1 – 826. The alignments on which this matrix is based were created using ClustalW. They are available upon request.

Hagens et al. BMC Cell Biology 2006 7:18   doi:10.1186/1471-2121-7-18

Open Data