Abi1 modulates Eps8-induced actin remodeling in a Rac-independent manner. Distribution of Eps8-myc (A,D), Abi1GFP (B), actin (C) revealed by phalloidin staining, and Rac (E,F) in Xenopus animal cap cells. (A-C) Simultaneous expression of Eps8 and Abi1 induce the formation of actin stars at the apical surface of superficial epithelial cells. (D-F) Endogenous Rac is not recruited to Eps8/Abi1-induced actin stars. (F) Eps8 is red and Rac is green in the merged image. Scale bar is equal to 10 μm in A,B and D-F and to 5 μm in C.
Roffers-Agarwal et al. BMC Cell Biology 2005 6:36 doi:10.1186/1471-2121-6-36