Cellular localization of various Tim50a proteins. Hela cells were transfected with GFP-tagged proteins (first column), followed by staining with antibody Y12 (second column) to detect Sm proteins (snRNPs). The merged image in color is shown in the last column (GFP is green, Sm proteins are red). Arrows mark speckles whereas arrowheads demarcate Cajal bodies. Note that cells for GFP-CAP50 and GFP-Tim50aN87 are shown at a lower magnification compared to the other images in order to demonstrate the cytoplasmic localization of these proteins.
Xu et al. BMC Cell Biology 2005 6:29 doi:10.1186/1471-2121-6-29