Effect of PBP10 on cytosolic calcium mobilization induced by peptide agonists. Neutrophil intracellular calcium mobilization was analyzed by monitoring Fura-2 fluorescence upon stimulation with the FPR agonist fMLF (100 nM; left) or the FPRL1 agonist WKYMVM (100 nM; right) in the absence (upper curves) or presence (lower curves) of PBP10 (1 μM). The curves are derived from a representative experiment. The calcium concentrations given in the right hand part of the figure are valid for the fMLF as well as the WKYMVM induced responses.
Fu et al. BMC Cell Biology 2004 5:50 doi:10.1186/1471-2121-5-50