Radial distribution of chromosomes 1 (red) and 8 (green) in nuclei of (a) multipotent precursor cells (n = 37), (b) myeloblasts (n = 27), (c) activated macrophages (n = 23) and (d) proerythroblasts (n = 40). Unlike in the median distribution used for determination of significance levels, in the graphs shown here all voxels of a segmented signal are represented. Chromosome 8 has only about one sixth of the size of chromosome 1. Accordingly, its interphase territories are much smaller, leading to a smaller sample of voxels and thus accounting for less smooth curves than for chromosome 1 territories, e.g. in myeloblasts. All curves for each chromosome are shown in one graph in a supplemental figure in additional file 1.
Stadler et al. BMC Cell Biology 2004 5:44 doi:10.1186/1471-2121-5-44