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Open Access Research article

Hypothesis: could the signalling function of membrane microdomains involve a localized transition of lipids from liquid to solid state?

Etienne Joly

BMC Cell Biology 2004, 5:3  doi:10.1186/1471-2121-5-3

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Question of Function

Klaus Fiedler   (2004-01-29 14:17)  Biozentrum, Basel, Switzerland email

I suggest that a biomembrane in a solid phase does not support biosynthesis and does not allow ion channel function. The latter is directly important for signaling and vesicular traffic.

Competing interests

None declared

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