Amino acid sequence alignment of plant and yeast VHA-a. Comparison of amino acid sequences deduced from the three coding regions detected in the A. thaliana genome, the sequence of M. crystallinum and the two yeast gene products Vph1 and Stv1 using ClustalW-algorithm. Identical amino acids are marked in dark grey, those similar with M. crystallinum in light grey. The programs JPRED (EMBL, Hinxton) and THMM (EBS, Denmark) were used to predict transmembrane domains (labelled with +). Amino acids identified as essential for H+-pumping in yeast are marked with *.
Kluge et al. BMC Cell Biology 2004 5:29 doi:10.1186/1471-2121-5-29