Figure 3.

Some fibroblast cell nuclei from the AD-EDMD patient 99-3 are negative for antibodies to lamin A/C. Immunolabelling of fibroblast cells with mutation LMNA R377H (a-c) and control cells (d-f) was done by using antibodies against emerin (a,d), lamin A/C (b,e) and lamin B (c,f). Not all nuclei stain for lamin A/C in patient cells (compare b with e). The corresponding phase-contrast images (a"-c"; d"-f") and Hoechst fluorescence (a'-c'; d'-f') are shown. Bars (c",f") 10 ┬Ám.

Reichart et al. BMC Cell Biology 2004 5:12   doi:10.1186/1471-2121-5-12
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