|
The effect of IGF-1 upon the developmental competence of in vivo fertilized mouse zygotes. |
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| Culture medium |
Total n |
Zygotes arrested in one-cell to morula stage (%) |
Zygotes developed to Blastocyst (%) |
|
|
|
||||
| Blastocyst (%) |
Hatched blastocyst (%) |
|||
|
|
||||
| kSOM/AA with IGF-1 |
106 |
12(11.3) |
94(88.7) * |
|
|
|
||||
| 43(40.6) ** |
51(48.1) ** |
|||
|
|
||||
| kSOM/AA without IGF-1 |
83 |
15(18.1) |
68(81.9) * |
|
|
|
||||
| 31(37.3) ** |
37(44.6) ** |
|||
|
IGF-1: 100 ng/ml. The results were pooled from 5 repeats of experiments. * P = 0.043 ** P > 0.05 | ||||
Lin et al. BMC Cell Biology 2003 4:14 doi:10.1186/1471-2121-4-14 |
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