Photomicrographs of decalcified (A and B) and methacrylate-embedded (C and D) femoral specimens. Cross-sections of normal mice show a normal marrow cavity (Fig. 2A) which is in sharp contrast to the appearance of the cross-section from an estradiol-treated mouse (Fig. 2B) in which only small islands of marrow are present. Localization of Ocl using tartrate-resistant acid phosphatase (TRAP) localization in metaphyseal bone from a normal mouse (Fig. 2C) and from an estradiol-treated mouse (Fig. 2D). (Fig. 2A and 2B, H&E, X 43; Fig. 2C and 2D, TRAP, X 640).
Gruber et al. BMC Cell Biology 2001 2:3 doi:10.1186/1471-2121-2-3